Article

Cell-autonomous and non-cell-autonomous effects of arginase-II on cardiac aging

2024-01-20

Abstract excerpt

Aging is a predominant risk factor for heart disease. Aging heart reveals low-grade chronic inflammation, cell apoptosis, cardiac fibrosis, and increased vulnerability to ischemic injury. The underlying molecular mechanisms responsible for the cardiac aging phenotype and its susceptibility to injury are far from being fully understood. Although previous literature reports a role of the mitochondrial enzyme arginas...

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Literature Corpus work: c951d763-755f-5488-a24c-b2c456b786cd
DOI: 10.1101/2024.01.17.576017

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