Article
Allelic loss at 1p34-36 predicts poor prognosis in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2000
Utada Y, Emi M, Yoshimoto M, Kasumi F, Akiyama F, Sakamoto G, Haga S, Kajiwara T, Nakamura Y
Abstract excerpt
Allelic losses of specific chromosomal regions in the DNA of tumor cells, which imply loss of tumor suppressor genes normally resident at those loci, may become useful postoperative prognostic indicators for breast cancers that have not yet metastasized to lymph nodes. To examine whether specific allelic losses might correlate with postoperative disease-free survival, we tested tumors from a cohort of 228...
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