Article
[Demonstration of two regions involved in chromosome 1p deletion in breast tumors].
Bulletin du cancer - 1 Feb 1994
Bièche I, Champème M H, Matifas F, Cropp C, Callahan R, Lidereau R
Abstract excerpt
Alteration of chromosome 1 is the most consistent cytogenetic abnormality found in human breast carcinoma. Cytogenetic studies have shown independent alterations on the two arms of chromosome 1; increased copy number of the long arm and loss of the short arm of chromosome 1. We carried out deleti...
Topics
- Alleles
- Breast Neoplasms
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- Chromosome Deletion
- Chromosome Disorders
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- DNA Probes
- Female
- Gene Amplification
- Genes, Tumor Suppressor
- Humans
