Article

A New Transgenic Tool to Study the Ret Signaling Pathway in the Enteric Nervous System

2022-06-13

Abstract excerpt

The receptor tyrosine kinase Ret plays a critical role in regulating enteric nervous system (ENS) development. Ret is important for proliferation, migration, and survival of enteric progenitor cells (EPCs). Ret also promotes neuronal fate, but its role during neuronal differentiation and in the adult ENS is less well understood. Inactivating RET mutations are associated with ENS diseases, e.g. Hirschsprung Disease...

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Literature Corpus work: c94094f6-987c-50a7-a90b-988a0ba319db
DOI: 10.20944/preprints202206.0165.v1

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