Article
A mouse model of TB-associated lung fibrosis reveals persistent inflammatory macrophage populations during treatment
2024-06-05
Abstract excerpt
Post-TB lung disease (PTLD) causes a significant burden of global disease. Fibrosis is a central component of many clinical features of PTLD. To date, we have a limited understanding of the mechanisms of TB-associated fibrosis and how these mechanisms are similar to or dissimilar from other fibrotic lung pathologies. We have adapted a mouse model of TB infection to facilitate the mechanistic study of TB-associated...
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Identifiers and source
- Literature Corpus work
- c93442ae-0b4e-5445-bab8-480908040d96
- DOI
- 10.1101/2024.06.04.597479