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Article

Murine models of pulmonary fibrosis: mechanisms, limitations and translational insights.

European respiratory review : an official journal of the European Respiratory Society - 1 Jul 2026

Lou Karen F, Fulcer McKenzie M, Lotesto Mary J, Davis Jennifer M, Ortiz Serrano Tatiana P, Ma Ruihua, Ridge Karen M

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible interstitial lung disease characterised by excessive collagen deposition, aberrant tissue remodelling, and impaired gas exchange, ultimately leading to respiratory failure and death. IPF carries a poor prognosis, with limited therapeutic options; currently approved treatments slow disease progression but do not reverse established...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42613079
DOI: 10.1183/16000617.0033-2026
PMCID: PMC13482731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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