Article
Molecular programs of fibrotic change in aging human lung
2021-01-19
Abstract excerpt
Aging is associated with both overt and subclinical lung fibrosis, which increases risk for mortality from viruses and other respiratory pathogens. The molecular programs that induce fibrosis in the aging lung are not well understood. To overcome this knowledge gap, we undertook multimodal profiling of distal lung samples from healthy human donors across the lifespan. Telomere shortening, a cause of cell senescenc...
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Identifiers and source
- Literature Corpus work
- ceb2c434-10bb-56ef-bb5c-1a2b78d55081
- DOI
- 10.1101/2021.01.18.427195