Article
Pulmonary Macrophages: A New Therapeutic Pathway in Fibrosing Lung Disease?
Trends in molecular medicine - 1 Apr 2016
Byrne Adam J, Maher Toby M, Lloyd Clare M
Abstract excerpt
Pulmonary fibrosis (PF) is a growing clinical problem which can result in breathlessness or respiratory failure and has an average life expectancy of 3 years from diagnosis. Therapeutic options for PF are limited and there is therefore a significant unmet clinical need. The recent resurgent interest in macrophage biology has led to a new understanding of lung macrophage origins, biology, and phenotypes. In this...
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