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Article

The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.

Psychiatry research - 30 Aug 2010

Montag Christian, Basten Ulrike, Stelzel Christine, Fiebach Christian J, Reuter Martin

Abstract excerpt

Mounting evidence shows that the brain derived neurotrophic factor (BDNF) plays a crucial role in depression and anxiety. The discovery of a functional variant of the BDNF gene--the BDNF Val66Met polymorphism--led to new insights into the molecular genetic mechanisms underlying these emotional disorders. Although there is evidence from animal research that the homozygous BDNF 66Met variant is associated with...

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Source

Identifiers

PMID: 20478625
DOI: 10.1016/j.psychres.2008.08.005

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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