Article

Regulation of eIF4F complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer

2016-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Targeted therapies that exploit the signaling pathways involved in prostate cancer are required to overcome chemoresistance and improve treatment outcomes for men. Molecular chaperones play a key role in the regulation of protein homeostasis and are potential targets to alleviate chemoresistance. Using image-based high content siRNA functional screening based on a gene expression signature, we i...

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Literature Corpus work: c9058f24-cd82-5744-9d62-b97ec926c5fa
DOI: 10.1101/096271

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