Article

Prostate cancer resistance leads to a global deregulation of translation factors and unconventional translation of long non-coding RNAs

2021-01-06

Abstract excerpt

<h4>ABSTRACT</h4> Emerging evidence associates translation factors and regulators to tumorigenesis. Recent advances in our ability to perform global translatome analyses indicate that our understanding of translational changes in cancer resistance is still limited. Here, we generated an enzalutamide-resistant prostate cancer (PCa) model, which recapitulated key features of clinical enzalutamide-resistant PCa. Usi...

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Literature Corpus work: ad37092f-f085-5cf2-9cdf-416ffb75bb12
DOI: 10.1101/2021.01.05.425492

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