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Article

Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer.

2024-08-18

Abstract excerpt

<h4>Background: </h4> The Androgen Receptor (AR) is crucial for prostate cancer (PCa) progression. Despite the introduction of second-generation AR antagonist, majority of patients develop resistance. The Serum Response Factor (SRF) was identified as a player involved in a crosstalk with AR signalling pathway and associated resistance. Elevated SRF levels in PCa patients were associated with disease progression an...

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Literature Corpus work
f6437d6d-6926-59e0-b376-ff5e6bd973ce
DOI
10.1101/2024.08.15.608046
Open publication

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Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer.DOI 10.1101/2024.08.15.608046
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