Article

Genome-wide association study in Heterogeneous Stock rats identifies genetic loci associated with aversion-based learning and cocaine aversion

2026-08-08

Abstract excerpt

Addiction is a complex and heritable trait which progresses through several developmental stages, each of which is presumably influenced by multiple partially overlapping genetic factors. Cocaine initially produces rewarding effects, followed by aversive effects including anxiety, craving, anhedonia, and withdrawal. These aversive effects have been suggested to contribute to the etiology of cocaine use disorders (...

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Literature Corpus work: 1a46430d-e383-5dc4-8228-10a6713a9a92
DOI: 10.64898/2026.08.07.743619

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