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Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats

2024-08-22

Abstract excerpt

<title>Abstract</title> <p>The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing to individual differences in OUD vulnerability. OUD shows strong heritability, however genetic variants contributing toward vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS)...

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Literature Corpus work
812872e2-0b8f-5e64-8f74-66eb9be6db6d
DOI
10.21203/rs.3.rs-4637892/v1
Open publication

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Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred ratsDOI 10.21203/rs.3.rs-4637892/v1
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