Article

Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats

2024-02-29

Abstract excerpt

The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing to individual differences in OUD vulnerability. OUD shows strong heritability, however genetic variants contributing to vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats to identify genes underlyi...

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Literature Corpus work: 0911fa33-dbf6-5f55-b8f1-d7774b3fe3e0
DOI: 10.1101/2024.02.27.582340

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