Article

GLP-1R agonist NLY01 reduces retinal inflammation, astrocyte reactivity, and retinal ganglion cell death secondary to ocular hypertension

2020-06-19

Abstract excerpt

<h4>SUMMARY</h4> Glaucoma is the leading cause of irreversible blindness worldwide and is characterized by the death of retinal ganglion cells. Reduction of intraocular pressure (IOP) is the only therapeutic mechanism available to slow disease progression. However, glaucoma can continue to progress despite normalization of IOP. New treatments are needed to reduce vision loss and improve outcomes for patients who...

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Literature Corpus work: 6274d0cb-665c-5f3e-8081-9d94c4adbcf8
DOI: 10.1101/2020.06.18.146720

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