Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution.

Nature ecology & evolution - 1 Sept 2023

Ma Wentai, Fu Haoyi, Jian Fanchong, Cao Yunlong, Li Mingkun

Abstract excerpt

Mutations in the SARS-CoV-2 genome could confer resistance to pre-existing antibodies and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a strong tendency for immune evasion, suggesting adaptive evolution. However, because previous studies have been limited to specific lineages or subsets of mutations, the overall evolutionary trajectory of SARS-CoV-2 and the underlying driving...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19
Share to Immune Evasion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to SARS-CoV-2

Source

Identifiers

PMID: 37443189
DOI: 10.1038/s41559-023-02123-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution.PMID 37443189Read ↗

Natural selection driven by escape from shifting antibody classes shapes SARS-CoV-2 evolutionSemantic proximity Read ↗

Immune Escape Associated with RBD Omicron Mutations and SARS-CoV-2 Evolution Dynamics.Semantic proximity Read ↗

Immune Escape Associated with RBD Omicron Mutations and SARS-CoV-2 Evolution DynamicsSemantic proximity Read ↗

Mutational analysis of SARS-CoV-2 variants of concern reveals key tradeoffs between receptor affinity and antibody escape.Semantic proximity Read ↗

The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution.Semantic proximity Read ↗

Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1Semantic proximity Read ↗

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasionSemantic proximity Read ↗

Predicting the mutational drivers of future SARS-CoV-2 variants of concern.Semantic proximity Read ↗

SARS-CoV-2 receptor binding mutations and antibody mediated immunitySemantic proximity Read ↗

Evolutionary trajectory of SARS-CoV-2 genome shifts during widespread vaccination and emergence of Omicron variantSemantic proximity Read ↗

Antibody evasion associated with the RBD significant mutations in several emerging SARS-CoV-2 variants and its subvariants.Semantic proximity Read ↗

SARS-CoV-2 evolution in the Omicron era.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.