Article

Histone Variant macroH2A1 Spatially and Functionally Organizes Human Papillomavirus Replication Foci in the Productive Stage of Infection

2021-07-27

Abstract excerpt

<h4>ABSTRACT</h4> The life cycle of HPV depends on keratinocyte differentiation as the virus modulates and takes advantage of cellular pathways to replicate its genome and assemble viral particles in differentiated cells. Viral genomes are amplified in nuclear replication foci in differentiated keratinocytes, and DNA repair factors from the DNA damage response signaling pathway are recruited to replicate viral DN...

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Literature Corpus work: c7ce065f-75ab-58c5-8cc8-ffe37371483b
DOI: 10.1101/2021.07.27.453825

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