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Human Papillomavirus E2 Protein: Linking Replication, Transcription, and RNA Processing

14 Jul 2016

Abstract excerpt

The human papillomavirus (HPV) life cycle is tightly linked to differentiation of the infected epithelium. This means that viral proteins must exert control over epithelial gene expression in order to optimize viral production. The HPV E2 protein controls replication, transcription, and viral genome partitioning during the viral infectious life cycle. It consists of a nucleic acid-binding domain and a...

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PMID: 27412596
DOI: 10.1128/jvi.00502-16

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