Article

Human papilloma virus (HPV) integration signature in Cervical Lesions: identification of MACROD2 gene as HPV hot spot integration site.

2022-07-22

Abstract excerpt

<title>Abstract</title> <p>Background High-risk HPV is clearly associated with cervical cancer. Integration of HPV DNA into the host genome is considered a key event in driving cervical carcinogenesis. However, the mechanism on how HR-HPV integration influences the host genome structure has remained enigmatic. Methods In our study, 25 DNA samples including 11 from fresh-frozen cervical carcinomas and 14 from fr...

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Literature Corpus work: 4f1d4f03-faa5-5c6d-b592-f7fbc411a401
DOI: 10.21203/rs.3.rs-1791974/v1

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