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Article

Chromatin assembly by the histone chaperone HIRA facilitates Human Papillomavirus replication

2025-09-05

Abstract excerpt

<h4>ABSTRACT</h4> The circular, double-stranded DNA genomes of Human papillomaviruses (HPV) exist in a nucleosomal state throughout the infectious cycle and rely on host histone epigenetic modifications and chromatin assembly processes to promote various phases of the viral life cycle. Here, we show that the histone H3.3 chaperone HIRA and its associated complex members are recruited to HPV replication factories...

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Literature Corpus work
2a08d808-ee06-5c16-96e0-4e5086c99501
DOI
10.1101/2025.09.05.674520
Open publication

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Chromatin assembly by the histone chaperone HIRA facilitates Human Papillomavirus replicationDOI 10.1101/2025.09.05.674520
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