Article

<i>IFIH1</i> rs1990760 variants, systemic inflammation and outcome in critically-ill COVID-19 patients

2021-07-07

Abstract excerpt

<h4>Rationale</h4> Outcomes in patients with severe SARS-CoV-2 infection (COVID-19) are conditioned by virus clearance and regulation of inflammation. Variants in IFIH1 , a gene coding the cytoplasmatic RNA sensor MDA5, regulate the response to viral infections. <h4>Objective</h4> To characterize the impact of IFIH1 rs199076 variants on host response and outcomes after severe COVID-19. <h4>Methods</h4> Pati...

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Literature Corpus work: c7c86953-bf10-5ebb-8f8e-6f46fa03d6a4
DOI: 10.1101/2021.07.03.21259946

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