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Genetic variations in Interferon-Induced with Helicase C Domain 1: Impact on COVID-19 risk and severity in the Moroccan population.

Human immunology - 1 Nov 2024

Aqillouch Safaa, Zerrad Chaimaa, Laazaazia Oumaima, Ouladlahsen Ahd, El Bissati Kamal, Akarid Khadija, Pineau Pascal, Benjelloun Soumaya, Ezzikouri Sayeh

Abstract excerpt

BACKGROUND: The clinical spectrum of COVID-19 varies considerably, ranging from asymptomatic cases to severe disease and even death. This variability can partly be attributed to genetic differences in genes associated with inflammation and immune responses. Among these genes, Interferon Induced with Helicase C Domain 1 (IFIH1), which codes for a cytoplasmic sensor, plays a crucial role in detecting SARS-CoV-2...

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PMID: 39342923
DOI: 10.1016/j.humimm.2024.111149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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