Article

Mapping pediatric brain tumors to their origins in the developing cerebellum

2021-12-20

Abstract excerpt

Understanding the cellular origins of childhood brain tumors is key for discovering novel tumor-specific therapeutic targets. Previous strategies mapping cellular origins typically involved comparing human tumors to murine embryonal tissues 1,2 , a potentially imperfect approach due to spatio-temporal gene expression differences between species 3 . Here we use an unprecedented single-nucleus atlas of the develop...

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Literature Corpus work: c783b3c9-cf4f-5391-9af9-566aa095e2fe
DOI: 10.1101/2021.12.19.473154

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