Article

Spatial mapping of pediatric brain tumors across diagnoses and relapses

2026-08-26

Abstract excerpt

We present a spatial transcriptomic atlas of 19 pediatric brain tumor patients spanning nine major and rare diagnoses, including seven relapses, revealing their spatial cellular and molecular organization. Each tumor section resolves into 2 - 4 recurrent spatial archetypes across 11 biological themes, with some mirroring developmental lineage patterns - for example, oligodendrocyte-lineage programs in pilocytic as...

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Literature Corpus work: d986d028-1f2b-5551-b72a-055efb1f3ce8
DOI: 10.64898/2026.08.25.746606

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