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Article

Mapping pediatric brain tumors to their origins in the developing cerebellum

2 Aug 2023

Abstract excerpt

BACKGROUND: Distinguishing the cellular origins of childhood brain tumors is key for understanding tumor initiation and identifying lineage-restricted, tumor-specific therapeutic targets. Previous strategies to map the cell-of-origin typically involved comparing human tumors to murine embryonal tissues, which is potentially limited due to species-specific differences. The aim of this study was to unravel the...

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Share to Fetal and Pediatric Neurological Disorders
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PMID: 37534924
DOI: 10.1093/neuonc/noad124

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