Article

MADDD-seq, a novel massively parallel sequencing tool for simultaneous detection of DNA damage and mutations

2023-08-27

Abstract excerpt

<h4>ABSTRACT</h4> Our genome is exposed to a wide variety of DNA-damaging agents. If left unrepaired, this damage can be fixed into mutations that promote carcinogenesis and the development of genetically inherited diseases. As a result, it is crucial that we can detect DNA damage and mutations with exquisite sensitivity. Here, we describe a modified version of double barcoding sequencing technology termed Mutati...

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Literature Corpus work: c7556454-a99e-50ea-8295-3f192c7d3dd9
DOI: 10.1101/2023.08.27.555013

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