Article

rad-51 downregulation redirects DNA repair and preserves genome stability in FANCD2-deficient Caenorhabditis elegans

2025-09-25

Abstract excerpt

<title>Abstract</title> Background Fanconi anemia is a rare genomic instability syndrome associated with congenital abnormalities and cancer predisposition. These alterations are mainly due to deficiencies in DNA repair mechanisms. The Fanconi anemia pathway is evolutionarily conserved, allowing functional studies in model organisms like Caenorhabditis elegans, where it promotes and executes error-free homolog...

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Literature Corpus work: c6f3a36d-2191-5da4-9026-e47c815dd7bd
DOI: 10.21203/rs.3.rs-7650970/v1

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