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Article

Caenorhabditis elegans dna-2 is involved in DNA repair and is essential for germ-line development.

FEBS letters - 4 Dec 2003

Lee Myon Hee, Han Sung Min, Han Ji Won, Kim Yun Mi, Ahnn Joohong, Koo Hyeon-Sook

Abstract excerpt

Caenorhabditis elegans germ cell proliferation and development were severely damaged in second generation dna-2 homozygotes. Even in the first generation, a much higher incidence of aberrant chromosomes in oocytes and resultantly higher embryonic lethality were found vs. wild type, when DNA breaks were induced by gamma-rays or camptothecin. The deficiency of dna-2 in combination with RNA interference on mre-11...

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Identifiers

PMID: 14644423
DOI: 10.1016/s0014-5793(03)01243-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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