Article

Loss of rad51 in zebrafish (Danio rerio) : a novel Fanconi anaemia model

2017-01-01

Abstract excerpt

RAD51 is an indispensable homologous recombination protein, necessary for strand invasion and crossing over. It has recently been designated as a Fanconi anaemia (FA) gene, following the discovery of two patients carrying dominant negative mutations. FA is a hereditary DNA repair disorder characterised by various congenital abnormalities, progressive bone marrow failure and cancer predisposition. The cellular and...

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Literature Corpus work: 4079f166-21d6-5754-a947-3e98e9a421d5
DOI: 10.17863/cam.17145

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