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Article

A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation.

Blood - 25 Aug 2016

Nestorowa Sonia, Hamey Fiona K, Pijuan Sala Blanca, Diamanti Evangelia, Shepherd Mairi, Laurenti Elisa, Wilson Nicola K, Kent David G, Göttgens Berthold

Abstract excerpt

Maintenance of the blood system requires balanced cell fate decisions by hematopoietic stem and progenitor cells (HSPCs). Because cell fate choices are executed at the individual cell level, new single-cell profiling technologies offer exciting possibilities for mapping the dynamic molecular changes underlying HSPC differentiation. Here, we have used single-cell RNA sequencing to profile more than 1600 single...

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Identifiers

PMID: 27365425
DOI: 10.1182/blood-2016-05-716480
PMCID: PMC5305050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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