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Power and precision: Evaluation and recommendations of quantitative trait analysis methods for RNA expression levels in the Hybrid Rat Diversity Panel

2022-07-14

Abstract excerpt

The Hybrid Rat Diversity Panel (HRDP) is a stable and well-characterized set of more than 90 inbred rat strains that can be leveraged for systems genetics approaches to understanding the genetic and genomic variation associated with complex disease. The HRDP exhibits substantial between-strain diversity while retaining substantial within-strain isogenicity, allowing for the precise mapping of genetic variation ass...

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Literature Corpus work
c6aeab7f-7c4e-549d-907a-57a85d6ce654
DOI
10.1101/2022.07.14.500105
Open publication

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Power and precision: Evaluation and recommendations of quantitative trait analysis methods for RNA expression levels in the Hybrid Rat Diversity PanelDOI 10.1101/2022.07.14.500105
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