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RatXcan: A framework for cross-species integration of genome-wide association and gene expression data

2022-06-05

Abstract excerpt

Genome-wide association studies ( GWAS ) have implicated specific alleles and genes as risk factors for numerous complex traits. However, translating GWAS results into biologically and therapeutically meaningful discoveries remains extremely challenging. Most GWAS results identify noncoding regions of the genome, suggesting that differences in gene regulation are the major driver of trait variability. To better i...

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Literature Corpus work
7cabef64-5a0d-58ef-a695-7be7acd8f8f3
DOI
10.1101/2022.06.03.494719
Open publication

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RatXcan: A framework for cross-species integration of genome-wide association and gene expression dataDOI 10.1101/2022.06.03.494719
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