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Article

Establishing the hybrid rat diversity program: a resource for dissecting complex traits.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2025

Dwinell M R, Takizawa A, Tutaj M, Malloy L, Schilling R, Endsley A, Demos W M, Smith J R, Wang S J, De Pons J, Kundurthi A, Geurts A M, Kwitek A E

Abstract excerpt

Rat models have been a major model for studying complex disease mechanisms, behavioral phenotypes, environmental factors, and for drug development and discovery. Inbred rat strains control for genetic background and allow for repeated, reproducible, cellular and whole animal phenotyping. The Hybrid Rat Diversity Panel (HRDP) was designed to be a powerful panel of inbred rats with genomic, physiological, and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39907792
DOI: 10.1007/s00335-024-10102-y
PMCID: PMC11880076

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