Article
Strategies for mapping and cloning quantitative trait genes in rodents.
Nature reviews. Genetics - 1 Apr 2005
Flint Jonathan, Valdar William, Shifman Sagiv, Mott Richard
Abstract excerpt
Over the past 15 years, more than 2,000 quantitative trait loci (QTLs) have been identified in crosses between inbred strains of mice and rats, but less than 1% have been characterized at a molecular level. However, new resources, such as chromosome substitution strains and the proposed Collaborative Cross, together with new analytical tools, including probabilistic ancestral haplotype reconstruction in outbred...
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