Article

Insight towards the effect of the multibasic cleavage site of SARS-CoV-2 spike protein on cellular proteases

2020-04-25

Abstract excerpt

Severe respiratory syndrome coronavirus 2 (SARS-CoV-2) infection presents an immense global health problem. Spike (S) protein of coronavirus is the primary determinant of its entry into the host as it consists of both receptor binding and fusion domain. While tissue tropism, host range, and pathogenesis of coronavirus are primarily controlled by the interaction of S protein with the cell receptor, it is possible t...

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Literature Corpus work: c68f7185-d08c-5bdf-90e5-8a515a176962
DOI: 10.1101/2020.04.25.061507

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