Article

Transcription directionality is licensed by Integrator at active human promoters

2023-07-26

Abstract excerpt

<title>Abstract</title> <p><bold>A universal characteristic of eukaryotic transcription is that the promoter recruits RNAPII to produce both precursor mRNAs (pre-mRNAs) and short unstable promoter upstream transcripts (PROMPTs) toward the opposite direction. However, how the transcription machinery senses the correct direction to produce pre-mRNAs is largely unknown. Here, through multiple acute auxin-inducible d...

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Literature Corpus work: c654163b-8092-54ad-981c-1425d61b72cd
DOI: 10.21203/rs.3.rs-3181116/v1

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