Article

Transcriptional Elongation-Associated RNA Processing Errors in Induced Cellular Growth Arrest

2025-06-23

Abstract excerpt

<h4>Summary Paragraph</h4> Transcription elongation factors control post-initiation steps of gene expression by RNA polymerase II (RNAPII). We have established distinct mechanistic roles for the essential elongation factors PAF1, NELF, SPT5, SPT6, and the Super Elongaiton Complex (SEC) via acute depletion of each individually in auxin-inducible degron lines. Here, we leverage these degron lines to explore the reg...

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Literature Corpus work: 33419f21-6b29-555a-b318-81a53b058e08
DOI: 10.1101/2025.06.23.660200

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