Article

Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information

2019-03-28

Abstract excerpt

Genome-wide association studies have generated an increasing number of common genetic variants that affect neurological and psychiatric disease risk. Given that many causal variants are likely to operate by regulating gene expression, an improved understanding of the genetic control of gene expression in human brain is vital. However, the difficulties of sampling human brain, and its complexity, has meant that bra...

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Literature Corpus work: c6252a47-ac74-5158-98ae-d72a103ca6a2
DOI: 10.1101/591156

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