Article

Gene specific effects on brain volume and cognition of<i>TMEM106B</i>in frontotemporal lobar degeneration

2024-04-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Objectives</h4> TMEM106B has been proposed as a modifier of disease risk in FTLD-TDP, particularly in GRN mutation carriers. Furthermore, TMEM106B has been investigated as a disease modifier in the context of healthy aging and across multiple neurodegenerative diseases. The objective of this study is to evaluate and compare the effect of TMEM106B on gray matter volume and cogni...

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Literature Corpus work: c6029ab8-785f-5be1-82dc-ff796bf8c166
DOI: 10.1101/2024.04.05.24305253

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