Article
Evaluation of biochemical algorithms to screen dysbetalipoproteinemia in ε2ε2 and rare APOE variants carriers.
Clinical chemistry and laboratory medicine - 29 Jan 2025
Michenaud Louise, Marrié Nathanaël, Rimbert Antoine, Marmontel Oriane, Charrière Sybil, Gibert Charles, Bouveyron Caroline, Mammi Jade, Cariou Bertrand, Moulin Philippe, Di Filippo Mathilde
Abstract excerpt
OBJECTIVES: Dysbetalipoproteinemia (DBL) is a combined dyslipidemia associated with an increased risk of atherosclerotic cardiovascular diseases mostly occurring in ε2ε2 subjects and infrequently in subjects with rare APOE variants. Several algorithms have been proposed to screen DBL. In this work, we compared the diagnostic performances of nine algorithms including a new one. METHODS: Patients were divided into...
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