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Article

Genetic risk score in patients with the APOE2/E2 genotype as a predictor of familial dysbetalipoproteinemia.

Journal of clinical lipidology - 1 Jan 2024

Satny Martin, Todorovova Veronika, Altschmiedova Tereza, Hubacek Jaroslav A, Dlouha Lucie, Lanska Vera, Soska Vladimir, Kyselak Ondrej, Freiberger Tomas, Bobak Martin, Vrablik Michal

Abstract excerpt

BACKGROUND: Familial dysbetalipoproteinemia (FD) is an autosomal recessive (rarely dominant) inherited disorder that is almost exclusively associated with the apolipoprotein E gene (APOE) variability. Nonetheless, only a small proportion of APOE2/E2 subjects develop the phenotype for mixed dyslipidemia; the context of other trigger metabolic or genetic factors remains unknown. METHODS: One hundred and one...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38044203
DOI: 10.1016/j.jacl.2023.11.010

Genes

APOE
APOA5
C3
ZPR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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