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Article

Diagnosis of Familial Dysbetalipoproteinemia Based on the Lipid Abnormalities Driven by APOE2/E2 Genotype.

Clinical chemistry - 1 Feb 2023

Bea Ana M, Cenarro Ana, Marco-Bened Victoria, Laclaustra Martn, Martn Csar, Ibarretxe Daiana, Pint Xavier, Arrobas Teresa, Vials Clara, Civeira Fernando, Olmos Salvador

Abstract excerpt

BACKGROUND: Familial dysbetalipoproteinemia (FDBL) is a monogenic disease due to variants in APOE with a highly variable phenotype. Current diagnostic lipid-based methods have important limitations. The objective is twofold: to define characteristics of dysbetalipoproteinemia (DBL) based on the analysis of APOE in patients from a lipid unit and in a sample from the general population, and to propose a screening...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36644927
DOI: 10.1093/clinchem/hvac213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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