Article
A microscopic landscape of the invasive breast cancer genome.
Scientific reports - 10 Jun 2016
Ping Zheng, Xia Yuchao, Shen Tiansheng, Parekh Vishwas, Siegal Gene P, Eltoum Isam-Eldin, He Jianbo, Chen Dongquan, Deng Minghua, Xi Ruibin, Shen Dejun
Abstract excerpt
Histologic grade is one of the most important microscopic features used to predict the prognosis of invasive breast cancer and may serve as a marker for studying cancer driving genomic abnormalities in vivo. We analyzed whole genome sequencing data from 680 cases of TCGA invasive ductal carcinomas of the breast and correlated them to corresponding pathology information. Ten genetic abnormalities were found to be...
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