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Low-Coverage WGS-Based CIN Scoring Enables Cost-Effective Molecular Stratification and Prognostic Risk Assessment in Laryngeal Squamous Cell Carcinoma

2026-01-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> To explore the feasibility of chromosomal instability (CIN) as a biomarker for molecular subtyping of laryngeal squamous cell carcinoma (LSCC) and to evaluate its correlation with clinical prognosis. <bold>Methods:</bold> This study included 38 patients with LSCC. Formalin-fixed paraffin-embedded (FFPE) tumor tissue samples were collected for low-coverage wh...

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Literature Corpus work
379a9568-e067-542e-be6a-e6252738dd1a
DOI
10.21203/rs.3.rs-8551894/v1
Open publication

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Low-Coverage WGS-Based CIN Scoring Enables Cost-Effective Molecular Stratification and Prognostic Risk Assessment in Laryngeal Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-8551894/v1
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