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Genetic and lipidomic identification of tuberculostearic acid as a controller of mycobacterial membrane compartmentalization

2022-08-18

Abstract excerpt

Mycobacteria diverge in a basic way from other bacterial and eukaryotic cells based on their distinct membrane structures. Here we report genome-wide transposon sequencing to discover the controllers of membrane compartmentalization in Mycobacterium smegmatis. cfa , a gene that encodes a putative cyclopropane-fatty-acyl-phospholipid synthase, shows the most significant effect on recovery from a membrane destabili...

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Identifiers and source

Literature Corpus work
c55d1b39-c249-5c59-b1ec-3dea3167229b
DOI
10.1101/2022.08.17.504266
Open publication

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Genetic and lipidomic identification of tuberculostearic acid as a controller of mycobacterial membrane compartmentalizationDOI 10.1101/2022.08.17.504266
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