Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in Mycobacteria

24 Jun 2019

Abstract excerpt

, the bacterium that causes the disease tuberculosis, is a complex structure composed of abundant lipids and glycolipids, including the signature lipid of these bacteria, mycolic acids. In this study, we identified two new components of the transport machinery that constructs this complex cell wall. These two accessory proteins are in a complex with the MmpL3 transporter. One of these proteins, TtfA, is required...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31239378
DOI: 10.1128/mbio.00850-19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two Accessory Proteins Govern MmpL3 Mycolic Acid Transport in MycobacteriaPMID 31239378Read ↗

MmpL3 is the flippase for mycolic acids in mycobacteriaSemantic proximity Read ↗

The Molecular Genetics of Mycolic Acid BiosynthesisSemantic proximity Read ↗

Cell Envelope Lipids in the Pathophysiology of Mycobacterium TuberculosisSemantic proximity Read ↗

Underestimated Manipulative Roles of Mycobacterium tuberculosis Cell Envelope Glycolipids During InfectionSemantic proximity Read ↗

The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune systemSemantic proximity Read ↗

Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities.Semantic proximity Read ↗

Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell EnvelopeSemantic proximity Read ↗

The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid.Semantic proximity Read ↗

Cell Surface Biosynthesis and Remodeling Pathways in Mycobacteria Reveal New Drug TargetsSemantic proximity Read ↗

The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence.Semantic proximity Read ↗

Genetic and lipidomic identification of tuberculostearic acid as a controller of mycobacterial membrane compartmentalizationSemantic proximity Read ↗

Comparative Genomics of Cell Envelope Components in MycobacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.