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Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?

21 May 2021

Abstract excerpt

Mycobacterial species, including Mycobacterium tuberculosis, rely on lipids to survive and chronically persist within their hosts. Upon infection, opportunistic and strict pathogenic mycobacteria exploit metabolic pathways to import and process host-derived free fatty acids, subsequently stored as triacylglycerols in the form of intrabacterial lipid inclusions (ILI). Under nutrient-limiting conditions, ILI...

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PMID: 34036305
DOI: 10.1093/femsre/fuab029

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