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Identifying Potential Drug Targets for the Treatment of Ulcerative Colitis Using Mendelian Randomization Combined with Co-localization Analysis

2024-03-28

Abstract excerpt

<h4>Purpose: </h4> To identify potential therapeutic targets for ulcerative colitis by integrating Mendelian randomization (MR) and Bayesian colocalization analysis to pinpoint gene expression quantitative trait loci (eQTLs) associated with ulcerative colitis risk. Methods Leveraging peripheral blood eQTL data from the eQTLGen Consortium and ulcerative colitis genome-wide association study (GWAS) summary statisti...

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Literature Corpus work
c54b2982-daa4-5240-9a28-a061c5b706d7
DOI
10.21203/rs.3.rs-4157703/v1
Open publication

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Identifying Potential Drug Targets for the Treatment of Ulcerative Colitis Using Mendelian Randomization Combined with Co-localization AnalysisDOI 10.21203/rs.3.rs-4157703/v1
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