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Article

Exploring inflammatory bowel disease therapy targets through druggability genes: a Mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Zhu Shuangjing, Lin Yunzhi, Ding Zhen

Abstract excerpt

Background: Inflammatory bowel disease is an incurable group of recurrent inflammatory diseases of the intestine. Mendelian randomization has been utilized in the development of drugs for disease treatment, including the therapeutic targets for IBD that are identified through drug-targeted MR. Methods: Two-sample MR was employed to explore the cause-and-effect relationship between multiple genes and IBD and its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38707907
DOI: 10.3389/fimmu.2024.1352712
PMCID: PMC11069403

Genes

GPBAR1
IL1RL1
PNMT
GPX1
PRKCB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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